Sodium Chloride (hypertonic) (Eye Drop / Eye Ointment)

Sodium Chloride (hypertonic) eye drops and ointments are medicines used to treat swelling of the cornea, the clear front part of your eye.

Drug class Hyperosmotic Agent
Type Single
Forms Eye Drop / Eye Ointment
Common strength 5% (drops), 6% (ointment)
Common Indian brands Sodium Chloride 5% eye drops / ointment (multiple generics)
Prescription status Prescription / OTC

What Sodium Chloride (hypertonic) is used for

Sodium Chloride (hypertonic) eye drops and ointments are prescribed to treat corneal oedema, which is swelling of the cornea. The cornea is the transparent, dome-shaped front surface of your eye that helps focus light. When it swells, it can become cloudy, leading to blurred vision and discomfort.

  • Fuchs’ endothelial dystrophy
  • Bullous keratopathy
  • After complicated cataract surgery

How it works

Sodium Chloride (hypertonic) works by drawing out excess water from your swollen cornea. Think of it like a very salty solution. When applied to the eye, this salty solution creates a difference in concentration, pulling the extra fluid out of the cornea. This helps to reduce the swelling, making the cornea clearer and reducing any associated pain or discomfort. By reducing the swelling, it helps improve your vision.

How it’s used

Always use Sodium Chloride (hypertonic) eye drops or ointment exactly as prescribed by your ophthalmologist. The typical dosing for eye drops is 1 drop, 4 to 6 times a day. For the eye ointment, it is usually applied at bedtime. This is because corneal swelling often tends to be worst when you wake up in the morning, and applying the ointment overnight can help manage this.

Your doctor will tell you the exact schedule and duration of treatment based on your specific condition. Do not stop using the medicine without consulting your doctor, even if your symptoms improve.

Always follow your ophthalmologist’s exact instructions.

Brands available in India

  • Sodium Chloride 5% eye drops / ointment (multiple generics)

Brand availability and pricing vary; confirm with your pharmacist.

Good to know

Prescription eye medicine — use only as directed by a qualified ophthalmologist. This page is for general education and is not a substitute for professional medical advice, diagnosis or a prescription. Do not self-medicate or reuse an old prescription.

Precautions & side effects

When you first instil Sodium Chloride (hypertonic) eye drops or apply the ointment, you might experience a stinging sensation. This is a common and expected side effect due to the salty nature of the solution, and it usually subsides quickly. It is not a cause for alarm unless it is severe or persistent.

It is particularly valuable to use this medicine in the morning, as corneal swelling often worsens overnight. Your doctor will provide specific instructions on when and how to use it for maximum benefit.

Remember, this is a prescription eye medicine. Use it only as directed by a qualified ophthalmologist. This page is for general education and is not a substitute for professional medical advice, diagnosis, or a prescription. Do not self-medicate or reuse an old prescription.

Understanding Corneal Oedema and Your Eyes

Your eyes are incredible organs, and the cornea plays a vital role in clear vision. The cornea is the transparent, outermost layer at the front of your eye, like a clear window. It helps to focus light onto the retina at the back of your eye, allowing you to see clearly. For the cornea to remain clear, it needs to maintain a very specific balance of fluid. Sometimes, due to various reasons, this balance can be disrupted, leading to an accumulation of fluid within the corneal layers. This condition is known as corneal oedema, or swelling of the cornea.

When the cornea swells, it can become cloudy or hazy, much like a fogged-up window. This cloudiness can lead to symptoms such as blurred vision, glare, halos around lights, and sometimes even discomfort or pain. Corneal oedema can be caused by several underlying conditions, including Fuchs’ endothelial dystrophy, a genetic condition where the cells responsible for pumping fluid out of the cornea gradually stop working effectively. It can also occur in conditions like bullous keratopathy, where blisters form on the corneal surface due to fluid accumulation, or sometimes as a complication after certain eye surgeries, such as complicated cataract surgery.

Understanding your condition is the first step towards managing it effectively. Your ophthalmologist will diagnose the specific cause of your corneal oedema and recommend the most appropriate treatment plan, which may include medicines like Sodium Chloride (hypertonic) eye drops or ointment to help reduce the swelling and improve your vision and comfort.

How to Correctly Use Your Eye Drops and Ointment

Proper application of eye drops and ointments is crucial for their effectiveness and to prevent contamination. Always wash your hands thoroughly with soap and water before touching your eyes or your medicine. If you wear contact lenses, remove them before applying eye drops or ointment, unless your doctor has specifically advised otherwise. Wait at least 15 minutes before reinserting them.

For eye drops: Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper directly over your eye, being careful not to touch your eye or any other surface with the tip of the dropper. Squeeze the bottle gently to release one drop into the pocket. Close your eye gently for a minute or two, without squeezing or blinking excessively, to allow the medicine to be absorbed. You can also press lightly on the inner corner of your eye (near your nose) to help prevent the drop from draining into your tear duct.

For eye ointment: After washing your hands, pull down your lower eyelid to create a small pocket. Squeeze a small amount of ointment (usually a thin strip about 1 cm long, or as directed by your doctor) into this pocket. Close your eye gently and roll your eyeball around to help spread the ointment. Your vision may be temporarily blurry after applying ointment, so it’s often best to use it before bedtime or when you don’t need clear vision immediately.

Always replace the cap tightly after use. Never share your eye drops or ointment with anyone else, even if they have similar symptoms, as this can spread infection.

General Eye Care, Storage, and When to Seek Medical Help

Maintaining good eye hygiene is essential, especially when you are using eye medicines. Always use fresh, clean tissues to blot any excess medicine from around your eyes. Avoid touching the tip of the eye drop bottle or ointment tube to your eye or eyelashes, as this can introduce germs into the medicine and lead to eye infections. If the tip does touch your eye, discard the bottle/tube and use a new one.

Store your Sodium Chloride (hypertonic) eye drops and ointment at room temperature, away from direct sunlight and moisture, as instructed on the packaging or by your pharmacist. Do not freeze the medicine. Keep all medicines out of the reach of children and pets. Check the expiry date on the bottle or tube and discard any expired medicine appropriately.

While Sodium Chloride (hypertonic) is generally safe and effective when used as directed, it’s important to know when to seek further medical advice. If you experience severe or persistent stinging, burning, redness, increased pain, or any new or worsening vision changes after using the medicine, contact your ophthalmologist immediately. Also, if your symptoms do not improve after a reasonable period, or if they worsen, you should consult your doctor. Always remember that your ophthalmologist is your best resource for managing your eye health and addressing any concerns you may have about your treatment.

Frequently asked questions

What is Sodium Chloride (hypertonic) used for?

Sodium Chloride (hypertonic) eye drops and ointments are used to treat corneal oedema, which is swelling of the cornea. This can occur in conditions like Fuchs' endothelial dystrophy, bullous keratopathy, or after complicated cataract surgery.

How does Sodium Chloride (hypertonic) work?

It works as a salty solution that draws excess water out of the swollen cornea. This process helps to reduce the swelling, improve the clarity of the cornea, and reduce any associated pain or discomfort.

What are the common brands of Sodium Chloride (hypertonic) in India?

Sodium Chloride (hypertonic) is available as Sodium Chloride 5% eye drops and ointment. There are multiple generic brands available in India.

How should I use Sodium Chloride (hypertonic) eye drops and ointment?

Typically, the eye drops are used 1 drop, 4-6 times a day. The ointment is usually applied at bedtime, as corneal swelling is often worst upon waking. Always follow your ophthalmologist's specific instructions for dosing and duration.

Do I need a prescription for Sodium Chloride (hypertonic)?

Sodium Chloride (hypertonic) is available both as a prescription medicine and over-the-counter (OTC). However, it is strongly recommended to use it only as directed by a qualified ophthalmologist for proper diagnosis and treatment of corneal oedema.

What precautions should I take when using Sodium Chloride (hypertonic)?

You might experience a stinging sensation when you first instil the medicine; this is expected. Morning use is particularly valuable because the cornea tends to swell overnight. Always use this medicine only as directed by your ophthalmologist and do not self-medicate.

References

  1. Corneal Conditions – National Eye Institute
  2. Eye health – MedlinePlus (US National Library of Medicine)
  3. Eye health information – American Academy of Ophthalmology
  4. Blindness and vision impairment – World Health Organization
  5. StatPearls – NCBI Bookshelf

Medically reviewed by , Chief Surgeon: Cornea, Cataract and Refractive Surgery — last reviewed 2026-07-28.

This page is for general education only and is not a substitute for professional medical advice, diagnosis or treatment. Never self-medicate or reuse an old prescription. Always consult a qualified ophthalmologist before starting, changing or stopping any eye medicine.

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