Latanoprostene Bunod + Timolol Eye Drops: Uses, Brands & Dosage

Latanoprostene Bunod + Timolol is an eye drop used to treat open-angle glaucoma when combination therapy is needed.

Drug class	Fixed-Dose Combination
Type	Combination
Forms	Eye Drop
Common strength	0.024% + 0.5%
Common Indian brands	Emerging combination
Prescription status	Prescription

What Latanoprostene Bunod + Timolol is used for

Latanoprostene Bunod + Timolol eye drops are prescribed to manage a specific eye condition:

Open-angle glaucoma: This medicine is used when your doctor determines that you need a combination therapy to effectively control your open-angle glaucoma.

Glaucoma is a group of eye conditions that damage the optic nerve, which is vital for good vision. This damage is often caused by abnormally high pressure in your eye. Open-angle glaucoma is the most common type, where the drainage angle for fluid in your eye remains open, but the fluid doesn’t drain properly, leading to a gradual increase in eye pressure. If left untreated, glaucoma can lead to irreversible vision loss.

By using Latanoprostene Bunod + Timolol as directed by your ophthalmologist at Pristine Eye Hospitals, you are taking an important step in managing your eye pressure and protecting your vision from further damage due to glaucoma.

How it works

Latanoprostene Bunod + Timolol is a combination eye drop that works in two main ways to reduce the pressure inside your eye:

Latanoprostene Bunod: This part of the medicine is a unique NO-donating prostaglandin. It helps to increase the outflow of fluid from your eye, thereby reducing the intraocular pressure.
Timolol: This is a beta-blocker. It works by reducing the production of fluid inside your eye.

By combining these two mechanisms, Latanoprostene Bunod + Timolol provides a more powerful effect in lowering eye pressure compared to using either medicine alone. This dual action is crucial for patients who need combination therapy to effectively manage their open-angle glaucoma and protect their optic nerve from damage.

How it’s used

Using your Latanoprostene Bunod + Timolol eye drops correctly is very important for their effectiveness. Please follow these instructions carefully:

Dosing: Instil 1 drop into the affected eye(s) once a day. Your doctor will tell you which eye(s) need treatment.
Timing: Try to use your eye drops at the same time each day to help you remember and maintain a consistent effect.
Important Step After Instilling: After you put the drop in your eye, gently press on the inner corner of your eye (near your nose) for 1-2 minutes. This technique helps to reduce the amount of medicine that gets absorbed into your body, which is especially important because this medicine contains a beta-blocker.
Do not stop suddenly: It is crucial not to stop using these eye drops suddenly without first talking to your doctor. Stopping abruptly can cause your eye pressure to rise again, potentially damaging your vision.
Prescription Medicine: Remember, this is a prescription medicine (Rx). Always use it exactly as prescribed by your ophthalmologist at Pristine Eye Hospitals.

If you are unsure about any step, please do not hesitate to ask your doctor or the healthcare team at Pristine Eye Hospitals for clarification.

Always follow your ophthalmologist’s exact instructions.

Brands available in India

Emerging combination

Brand availability and pricing vary; confirm with your pharmacist.

Please note

Contains a beta-blocker that can be absorbed into the body. Tell your doctor if you have asthma, COPD, a slow heart rate or heart disease. After instilling, gently press the inner corner of the eye for 1-2 minutes to reduce absorption. Do not stop suddenly without advice.

Precautions & side effects

Latanoprostene Bunod + Timolol is an emerging combination medicine, and it’s important to be aware of certain precautions, especially because it contains a beta-blocker. Your doctor at Pristine Eye Hospitals will discuss these with you, but here are key points to remember:

Beta-blocker Warning: This medicine contains a beta-blocker that can be absorbed into your body. This means it can affect other parts of your body, not just your eyes.
Tell Your Doctor About Existing Conditions: It is extremely important to tell your doctor if you have any of the following conditions before starting this medicine:
- Asthma: Beta-blockers can worsen asthma symptoms.
- COPD (Chronic Obstructive Pulmonary Disease): Similar to asthma, beta-blockers can affect breathing in individuals with COPD.
- Slow Heart Rate (Bradycardia): Beta-blockers can further slow down your heart rate.
- Heart Disease: If you have any form of heart disease, your doctor needs to know, as beta-blockers can impact heart function.
Do Not Stop Suddenly: Never stop using these eye drops suddenly without consulting your doctor. Abruptly stopping beta-blockers can have adverse effects on your heart and can also cause your eye pressure to increase, potentially leading to further vision damage.
Reducing Systemic Absorption: As mentioned in the ‘How to Use’ section, gently pressing the inner corner of your eye for 1-2 minutes after instilling the drop is very important. This helps to reduce the amount of medicine absorbed into your bloodstream, minimizing potential body-wide effects.
Other Medications: Always inform your doctor about all other medicines you are taking, including over-the-counter drugs, supplements, and herbal remedies, to avoid potential interactions.
Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your doctor before using this medicine.
Driving and Operating Machinery: After instilling eye drops, your vision might be temporarily blurred. Wait until your vision clears before driving or operating machinery.

Your doctor will weigh the benefits and risks of this medicine for your specific condition. Always follow their advice and report any new or worsening symptoms promptly.

Understanding Glaucoma and Why Treatment is Essential

Glaucoma is a serious eye condition that can lead to irreversible vision loss if not managed properly. It’s often called the ‘silent thief of sight’ because it usually progresses without noticeable symptoms in its early stages. The most common type, open-angle glaucoma, involves a gradual increase in the pressure inside your eye (intraocular pressure). This elevated pressure damages the optic nerve, which is responsible for sending visual information from your eye to your brain. Once the optic nerve is damaged, the vision loss cannot be restored. This is why regular eye check-ups, especially if you have risk factors like a family history of glaucoma, diabetes, or are over 40, are crucial for early detection. When diagnosed, medicines like Latanoprostene Bunod + Timolol are prescribed to lower this eye pressure, thereby protecting your optic nerve from further damage and preserving your vision. It’s a lifelong condition for most, meaning consistent and correct use of your prescribed eye drops is vital for maintaining your eye health.

Correct Eye Drop Instillation and Hygiene

Proper technique for applying eye drops is essential to ensure the medicine works effectively and to prevent contamination. Here’s a step-by-step guide:

Wash Your Hands: Always start by thoroughly washing your hands with soap and water to prevent introducing germs into your eye.
Check the Dropper: Ensure the dropper tip is clean and not damaged. Do not let the tip touch any surface, including your eye or fingers, to avoid contamination.
Prepare for Instillation: Gently pull down your lower eyelid with one finger to create a small pocket.
Tilt Your Head: Tilt your head back slightly and look upwards.
Instil the Drop: Hold the bottle upside down with the dropper tip pointing towards your eye. Squeeze the bottle gently to release one drop into the pocket you created in your lower eyelid. Be careful not to touch your eye with the dropper tip.
Close Your Eye and Press: Gently close your eye. Do not blink or squeeze your eye shut. Immediately after, gently press on the inner corner of your eye (near your nose) with your finger for 1-2 minutes. This is a very important step for Latanoprostene Bunod + Timolol, as it helps prevent the medicine from being absorbed into your bloodstream and reduces potential side effects.
Wipe Excess: Use a clean tissue to gently wipe away any excess liquid around your eye.
Wash Hands Again: Wash your hands again to remove any medicine.

If you are using other eye drops, wait at least 5-10 minutes between different medications to allow each drop to be absorbed properly. Store your eye drops as advised by your pharmacist or doctor, usually in a cool, dry place, away from direct sunlight and out of reach of children. Always check the expiry date and discard the bottle after the recommended period, even if there’s medicine left, to prevent infection.

When to Seek Medical Help

While Latanoprostene Bunod + Timolol is an important medicine for managing your glaucoma, it’s crucial to know when to contact your doctor at Pristine Eye Hospitals. You should seek immediate medical attention if you experience any sudden changes in your vision, severe eye pain, redness, or swelling around your eyes. These could be signs of an infection, an allergic reaction, or another serious eye condition that requires prompt evaluation. Also, if you notice any new or worsening symptoms that you suspect are related to your eye drops, such as persistent eye irritation, changes in your heart rate, difficulty breathing, or any other unusual body-wide effects, please inform your doctor immediately. Remember, never stop your glaucoma medication without consulting your ophthalmologist, as this can lead to a dangerous increase in eye pressure. Regular follow-up appointments with your doctor are essential to monitor your eye pressure and overall eye health, ensuring your treatment plan remains effective and safe for you. Your well-being is our priority at Pristine Eye Hospitals, and we are here to support you every step of the way in managing your glaucoma.

Frequently asked questions

What is Latanoprostene Bunod + Timolol used for?

Latanoprostene Bunod + Timolol eye drops are used to treat open-angle glaucoma in patients who require combination therapy to manage their eye pressure effectively.

How does Latanoprostene Bunod + Timolol work?

This medicine works in two ways: Latanoprostene Bunod increases the outflow of fluid from your eye, and Timolol, a beta-blocker, reduces the production of fluid inside your eye. This dual action helps to lower the pressure inside your eye.

What are the common Indian brands for Latanoprostene Bunod + Timolol?

Latanoprostene Bunod + Timolol is currently an emerging combination, so specific widely recognized Indian brands may not yet be established. Your doctor will prescribe the appropriate formulation.

How should I use Latanoprostene Bunod + Timolol eye drops?

You should instil 1 drop into the affected eye(s) once a day. After instilling the drop, gently press on the inner corner of your eye for 1-2 minutes to reduce absorption into your body. Do not stop using it suddenly without your doctor's advice.

Do I need a prescription for Latanoprostene Bunod + Timolol?

Yes, Latanoprostene Bunod + Timolol is a prescription medicine (Rx) and must only be used under the guidance of a qualified ophthalmologist.

What are the key precautions I should be aware of when using Latanoprostene Bunod + Timolol?

This medicine contains a beta-blocker that can be absorbed into the body. It is crucial to tell your doctor if you have asthma, COPD, a slow heart rate, or heart disease. Also, do not stop using the eye drops suddenly without your doctor's advice.

References

Medically reviewed by Dr. C Jagadesh Reddy, Chief Surgeon: Cornea, Cataract and Refractive Surgery — last reviewed 2026-07-28.

This page is for general education only and is not a substitute for professional medical advice, diagnosis or treatment. Never self-medicate or reuse an old prescription. Always consult a qualified ophthalmologist before starting, changing or stopping any eye medicine.